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Systematic Review

Transcript: Affordable Housing Policy How effective are current U.S. policy trends in addressing affordable housing needs? Lindsey Freeburn PUAD 5008 Summer 2020 Overview Result of the Great Depression High density, public housing developments 420,000 units developed between 1937 and 1957 Major Critiques Concentrated poverty, limited resources, rapid decline in conditions Policy Alternatives Private developments, public funding Poverty Dispersion (Recent Trend) Inward (Project-based assistance): Mixed-Income Developments/Re-developments Outward (Tenant-based assistance): Housing Vouchers & Tax Credits Brief History Research Question 1. How effective are poverty-dispersion based policies at addressing the affordable housing needs in the United States? 2. What are the main implications and considerations for policymakers when implementing poverty-dispersion based policy decisions? Methods Systematic Review Auraria Library & Google Scholar Two-stage search Search 1 Develop list of key terms & policy names Search 2 Identify relevant policy intervention evaluations Inclusion Criteria Results from Search 1: Inclusion Criteria Specific Inclusion Criteria: Peer-reviewed academic literature Post 2010 United States Context Policy focus Empirical studies Relevancy to criteria and terms from Search 1 Systematic Search Search 2 Started with 57,826; Ended with 13 Results Results Key Findings Key Findings Poverty-dispersion policies demonstrate positive and wide-ranging effects on neighborhood characteristics and living conditions for tenants. Crime reduction, increased diversity, increased housing values, increased housing quality and safety High-quality methods [RCT & QED]; supported by additional medium-quality methods Main implications and considerations: Often generate tensions and inequities Racial Economics Reduced low-income housing availability Displacement and gentrification Policy Implications Actively Mitigate Tensions and Inequities Support additional assistance programs and resources Policy Implications Support Efforts Cautiously Means of investing in neighborhoods and improving quality of life Prevent Displacement Localized assessments needed to determine low-income housing capacity References

Systematic Review

Transcript: Defining Eligibility Criteria Inclusion Criteria: 1. Population: HIV positive patients age <18, both receiving treatment and not receiving treatment 2. Study Setting: resource limited settings 3. Language: no language restrictions 4. Intervention: Nutritional supplementation (food, protein/energy supplements, or micronutrients) 5. Study Design: Before/after interventions, cohort studies, randomized controlled trials, 6. Outcomes: anthropometrics, frequency of co-morbid infections/conditions (such as TB, candidiasis, PCP), HIV-related disease staging, or mortality rates. 7. Source of article: Studies in reported in peer-reviewed journals and non-published clinical trials. Exclusion Criteria: 1. No studies repeating the cohort population 2. Studies that focus on breastfeeding and the HIV transmission Finding the right terms to search: Search online bibliographic databases, including MEDLINE, EMBASE, The Cochrane Collaboration and Clinical Trials Databases, Google scholar, relevant websites (such as the WHO and International AIDS Society) and bibliographies of pertinent articles. Use search terms: OVID Combination of [HIV or HIV infection or AIDS](exp) AND ([food or nutritional physiological phenomena](exp) AND ([newborn]/lim OR [infant]/lim OR [preschool]/lim OR [school]/lim OR [child]/lim OR [adolescent]/lim) EMBASE Combination of [HIV or HIV infection or AIDS](exp) AND ([nutrition or nutritional disorder or nutritional science](exp) ([newborn]/lim OR [infant]/lim OR [preschool]/lim OR [school]/lim OR [child]/lim OR [adolescent]/lim) Find All Relevant Articles: Search Strategy - Quality of the systematic review depends on the quality of the identified studies - Effective strategies depend on a clearly articulated research question - Balance need for sensitivity (comprehensive) vs. specificity (precision) of retrieval - Strategies must take into account the unique structure and search function of each database - Reach out to topic specific Ruth Lilly Medical Librarians Identifying relevant studies - Search of MEDLINE and other computerized literature databases - Hand Searching: Checking reference lists Checking other reviews Print versions of electronic databases Hand searches of appropriate journals Identifying unpublished studies Contact authors Trial registries Conference abstracts My PICO Question: Thank you for listening! Among HIV-infected pediatric patients (< 18years of age) in resource-limited settings, does receiving nutritional supplementation improve health outcomes when compared to those who do not receive nutritional supplementation. ...then you see if anyone else has asked the same question. Developing your protocol Defining a Research Question - Developed before starting the review to serve as a road map - Publication of the protocol prior to starting - PRISMA guidelines - Registries - Cochrane - Campbell - PROSPERO (Prospective Register of Ongoing Systematic Reviews) - Formulate an important, well-focused question - Consider 4 basic components: PICO - Population - Intervention / Exposure - Comparison - Outcomes - Guides the entire process - Defines criteria for identifying candidate studies Extracting Data Lessons Learned: Extract data independently and then discuss Make a table for comprehensive data needed from each study Will likely be used in manuscript Helps you organize your data for analysis Some studies have no usable data but still met pre-defined criteria still must be included. Must report excluded studies and why these were excluded Extracting Data: Methods Overview - Define the question - Define eligibility criteria - Find ALL the relevant studies - Extract data - Assess study quality - Analyze and present results - Interpret results Must be explicit to ensure reproducibility Must be systematic in order to reduce bias - Use technology to help you - Save the search criteria and date search performed - Systematic review software (RevMan, Covidence, Excel) - Bibliographic management software (Endnote, Zotero, Mendeley) - Remove duplicates - Document EVERYTHING - Be very careful in choosing your systematic review team - Think about your timeline and try not to get behind - Consider re-running your search if there is a delay in your initial search and manuscript submission - Err on the side of generalizing certain inclusion criteria if you are unsure of the level of specificity you are including - Document everything Why you should consider performing a systematic review: - requires few resources - may advance and inform clinical decision making - can help lay groundwork for later research - you can be an expert in a particular topic - very publishable Analyze and present results Interpret results Types of Systematic Reviews: Qualitative- results of studies are summarized but not statistically combined Quantitative- statistical methods used to combine the results of two or more studies Meta-analysis- a specialized review that uses statistical methods to pool estimates of effect from

Systematic Review

Transcript: Sub-keywords Sub-keywords Description Asset library - Student Centered pedagogy - Active pedagogy - Innovative Pedagogy - Adult learning - Experiential learning - Professional Learning Communities (PLC) Describe to art and science of teaching, involving the set of teaching practices, strategies, and techniques that teachers use to help students learn. Professional Learning Communities (PLC) Description Go into detail here Describe to collaborative approach involves teachers working together to achieve common goals, share expertise, and engage in continuous learning and improvement. Add another thought here Sources Sub-keywords - Grassroots - Relationships - Tangible Sources Pedagogy in education Watkins and Mortimore (1999) Lingard er al., (2003) Dumont, Isrtance & Banevides (2010) Huber, J., & Europe, C. O. (2012) Weston, D., & Clay, B. (2018) Hipp, K. K., & Huffman, J. B. (2003) Sources Description Sources Description Johnstone, K. (2017) Widjaja, W., Vale, C., Groves, S., & Doig, B. (2017) Park, S., & Gentry, V. (2017) Monica, S. (2023) Foster, G. O. N. D. W. E. (2021) Emphasizes the ongoing learning process of teachers, involving both formal and informal education to enhance teaching skills and student learning outcomes. Alejandro, P., & David, I. (2018) Educational Sciences (2023) Fernández-Batanero et al., (2023) Is rooted in teachers' professionalism and is seen as a problem-solving process, shifting the perception of teachers from technicians to experts in the art and science of teaching Sub-keywords Sub-keywords Teacher Professional Development (TPD) Innovative Pedagogy - Adult learning - Experiential learning - Learning form Communities - Digital Competence - Digital Transformation - Digital Teaching Skaills Sub-keywords Sub-Keywords - Connectivism - Positive learning environment - Motivate the learners - Power - Trust - Quality Gamification in Education School Leadership Systematic Review Description Description Refers to the integration of elements of game-design elements into educational environments to engage and motivate students Emphasizes the importance of critical reflection, the development of a shared vision focused on equity, and the use of transformative dialogue to advance equality within schools on a global scale. By: Leonie (p6620584) Sources Sources Ward et al. (2014), Brown (2004), Shields (2010), Raffo and Gunter (2008), Yukl, G., William L., & Gardner III (2019a). Educational Sciences (2023) Alejandro, P., & David, I. (2018) Dias, L. P. S., Barbosa, J. L. V., & Vianna, H. D. (2018) Xu, W. (2020).

Systematic Review

Transcript: http://blogs.gartner.com/svetlana-sicular/data-scientist-mystified/ Proforma utilized that Centre for Reviews and Dissemination created to ensure a summary table was properly filled out and that information was taken systematically. Once eligibility was determined, more data was extracted from article. Quality assessment was then completed before the article was included in the study. Strengths and Limitations of Sample Identified (Moorcroft et al., 2011) Quality Appraisal Not necessary because meta-analysis was not used. Introduction (Moorcroft et al., 2011) (Moorcroft et al., 2011) Information that was extracted included study methodology, quality, sample selection, blinding, population characteristics, setting of study, exposure, baseline measurements, outcome measurements, and findings. Also, length of follow-up, completing of follow-up, missing data, statistical analysis, and presentation of results was collected. Meta-analysis Was Not Performed, Was There Adequate Justification For Using a Narrative Integration Method? Implications for Nursing Practice and Further Research Clearly Stated Adequate Information About Sample Characteristics and Findings Extracted Data extraction (Moorcroft et al., 2011) The Report Clearly Described Criteria for Selecting Primary Studies (Moorcroft et al., 2011) -Guidance from Critical Appraisal Skills Programme, Scottish Intercollegiate Guidelines Network, School of Health and Related Research, Centre for Reviews and Dissemination, and Oxman and Guyatt were used for critical appraisal. -A defensible and well-defined set of criteria was used - Design, methods, participants, setting, bias, key measures, and variables assessed (Polit & Beck, 2012) Information extracted about methodologic and administrative aspects of study Information about sample characteristics and findings extracted Steps taken to enhance integrity of dataset (Moorcroft et al., 2011) Data was put into tables and put together based upon when solid foods were introduced, and then when the obesity rate was measured. (Moorcroft et al., 2011) Quality 16 papers were excluded based on low quality assessment Quantity 24 studies, 34000 participants Consistency Majority showed no association. The studies that did either did not have a significant difference, did not include breastfeeding, or did not relate height Search Strategy (Moorcroft et al., 2011) Scope and Importance Conclusions BMI is not always a good indicator for being overweight and this is what most of the studies used. Most studies relied on memory recall of when solids were introduced. Publication bias could have occurred since only electronic data bases were included. Developing countries were not included in this study, even though obesity is a global issue. Outcome measurements to determine if the participants were overweight differed. Most studies were small, but together they showed a large sample size (Moorcroft et al., 2011) http://www.actbucks.org.uk/research.html The Reviewers Appraised the Quality of Primary Studies as Evidence With Good Quality http://www.webgnomes.org/blog/10-seo-analysis-tools/ The scope of the project is appropriate as obesity is one of the leading public health concerns worldwide. The topic of the review is important for nursing due to the fact that obesity is a risk factor for diabetes, some cancers, cardiovascular disease, and musculoskeletal disorders (Moorcroft et al., 2011). As nurse practitioners, prevention strategies should be implemented with each individual case to prevent such diseases. Nurses should educate patients about health promotion for healthy eating habits. Issue of Publication Bias Adequately Addressed Nurses should continue to recommend current WHO recommendations and include healthy eating practices per the results of this study. No specific further research was suggested, but a whole family approach to obesity prevention and education that includes genetics and environment was recommended. -Criteria reasonable as initial search began as early as 2007 and later updated in 2008 and 2010. -No date restrictions were applied until the updated research began. Studies approved for use were of those participants living in developed countries. -Studies also used had to be randomized, observational, and case-controlled. 17 million people die per year from cardiovascular disease At age 4-5,24% of boys and 21.5% of girls are overweight or obese At age 10-11, 34.5% of boys and 30.7% of girls are overweight or obese Systematic Review Tables, Figures, and Text Used Effectively to Summarize Findings (Moorcroft et al., 2011) Analysis of Data Thorough and Credible Appraised quality of studies used Appraisals done by two reviewers Appraisal information used in well defined and defensible manner in result analysis Crystal Lillibridge & Sabrina Meza NUR/518 December 6, 2013 Dr. Patricia Shannon http://ts-1.eee.hku.hk/ccst9015sp13/p03/conclusions-and-recommendations/ Study designs, duplicate reports, topic of

Systematic Review

Transcript: A Systematic Review & Meta-analysis Exercise as a Treatment for Venous Leg Ulcers Adi Haupt, Bradyn Parker, Chloe Badger, Gabrielle Newman, Natasha Qazi Introduction: Venous Leg Ulcers (VLU) Introduction: Venous Leg Ulcers (VLU) Definition and symptoms: VLUs are painful, debilitating, frequently recurring active ulcers on the lower limb lasting 4 weeks or more. Causes: VLUs disease is multifactorial. It occurs due to a blockage in the venous system, causing improper venous return, elevated venous pressure, and turbulent venous flow, ultimately leading to decreased calf muscle pump function Diagnosis: Medical history and clinical examinati... Diagnosis: Medical history and clinical examination: measurements of brachial pressure, ambulatory venous pressure and superficial venous reflux. 1. Nazarko L. British J. Com. Nurs. 2016;21:S8-S14. 2. Rice JB, et al. J. Med. Eco. 2014;17(5):347-56. Usual treatment: Compression dressings with active components, drug therapies, and venous surgery Usual treatment: Compression dressings with acti... Burden of the disease: VLUs largely impact the community due to the high prevalence and reccurence, financial burden, slow healing rate, need for multidisciplinary care team and overall impact on patients’ quality of life. 1. Lazarus G, et al. Wound Rep. & Reg. 2014;22(1):34-42. PICOS PICOS This review aims to assess the benefits of exercise as a treatment in addition to standard compression therapy for venous leg ulcers in adult patients. Aims: Aims: Electronic searches of three databases were performed: 1. Medline 2. Proquest 3. Web of Science Three search strategies: Exercise key words Ulcer key words Trial key words Methods: Search Strategy Methods: Search Strategy 1. Applied PICOS criteria to studies 2. Extraction of outcome data 3. Assessed risk of bias of included studies 4. Measures of treatment effects 5. Meta-analysis Data Extraction Data Extraction Results Results Prisma Flowchart Prisma Flowchart Characteristics of Included Studies Characteristics of Included Studies All studies open label RCTs Average age of 60 years Severity of disease similar among studies Outcomes greatly varied between studies All studies reported adverse events and proportion of participants with healed ulcers 3 studies focused on heel raises for exercise & 2 focused on walking All studies had compression bandaging as a comparator Bias Assessment Bias Assessment Meta-analyses Meta-analyses Only some outcomes could be analysed Significant methodological heterogeneity Poor reporting of results Four meta-analyses performed Meta-analysis Figure 1: Meta-analysis of number of patients with healed ulcers at 12 weeks Figure 2: Meta-analysis of change in ejection fraction Meta-analyses Meta-analysis Meta-analysis Meta-analyses Figure 3: Meta-analysis of adverse events Figure 4: Meta-analysis of patient withdrawals Meta-analysis Conclusion Conclusion Primary outcomes = no significant benefit or harm Secondary outcomes = significant increase in ejection fraction, which may reduce venous insufficiency and lead to improved VLU healing. 2 ongoing studies with different outcomes and exercise type = may affect results Unreliable evidence: Inconsistent reporting Neglect to report all primary outcomes, Bias: small sample sizes, inadequate blinding, heterogenous outcomes and intervention type. Cannot either recommend or discourage the addition of exercise therapy to current gold standard. Implications Implications Implications Conform to recommendations of Consolidated Standards of Reporting Trials guidelines (1). Implications be comprehensive ensure adherence (and include reasons for non-adherence) clearly and fully report : baseline characteristics, wound size, healing rate and reoccurrence investigate different venous ulcer aetiology and exercise therapies be conducted over longer timeframes Need future trials to:

Systematic Review Presentation

Transcript: By: Emily Amayreh, Megan Matthews, Lily Watson What are health professionals feelings and attitudes towards working with the Alzheimer’s population? Sample Relevant Literature Sullivan and Muscat (2005) Used Alzheimer's Disease Knowledge test Found that carers of persons with AD know twice as much about AD than non-carers. The authors concluded that there is a need for public education on AD. Padilla (2011) Outlines four main principles about the ethical care of service professionals Recognizing and being attentive to others Taking responsibility for action Performing caring work competently Being responsive to care receivers’ position or considering care from their perspective Alzheimer’s Disease is predicted to double every 20 years. Friends and family care for approximately 70% of people with AD in their home. Care of people with AD is extremely resource demanding and has a great impact on formal and informal caregivers. Hogan, Lisy, Savannah, Henry, Kuo, & Fisher (2003) Found 6 themes from their data: 1. "I feel guilty leaving her" 2. "Our roles have been reversed" 3. "Adapt...to what you are going through" 4. I have to cook, I have to clean...I am always busy" 5. "Some people shy away" 6. "My health care comes after his" Themes: 1. Rewarding 2. Hardest part is seeing the client suffer 3. Elicits emotions of anger and frustration 4. Unpredictable Our sample included: 1. An occupational therapist who has been working with this population for 7 years 2. A nurse who has been caring for her mother with Alzheimer's for 2 years 3. Blog describing the impact of caring for a family member with Alzheimer's: Title: Caregiving, Mothering Mother, and More: A blog about the guilt, frustrations, humor, and sweet times that come with caregiving with a focus on Parkinson's and Alzheimer's Author: Carol D. O'Dell Limitations and Recommendations Methodology Findings Systematic Review Presentation Relevant Literature References Padilla, R. (2011). Effectiveness of Occupational Therapy Services for People with Alzheimer’s Disease and Related Dementias. American Journal of Occupational Therapy. 65(5). Sullivan, K. & Muscat,T. (2005). Attitudes towards the diagnosis of Alzheimer's disease among carers and non-carers. International Journal of Therapy and Rehabilitation, 12(9), 379-386. C. O'Dell. (2013, January 4). Caregiving firsts, starting a new day or a new year [Web log comment]. Retrieved from http://caroldodell.wordpress.com/page/3/ C. O'Dell. (2012, October 29). How to be a friend to someone who has dementia/alzheimer's. Retrieved from http://caroldodell.wordpress.com/page/3/ C. O'Dell. (2012, August 29). "I need You-I don't need you:" The push-pull of caregiving. Retrieved from http://caroldodell.wordpress.com/page/3/ C. O'Dell. (2012, April 23). Laughter and sleep, a caregiver's best defense against depression and stress. Retrieved from http://caroldodell.wordpress.com/page/3/ C. O'Dell. (2012, May 11). Need a safe place to vent, ask questions, and let it all out? Caregivers need to talk to other caregivers. Retrieved from http://caroldodell.wordpress.com/page/3/ Hogan, V.M., Lisy, E.D., Savannah, R.L., Henry, L., Kuo, F., & Fisher, G.S. (2003). Role change experienced by family caregivers of adults with alzheimer's disease: Implications for occupational therapy. Physical & Occupational Therapy in Geriatrics, 22(1), 21-43. doi: 10.1300/J148v22n01_02 Participants were selected based on their experience working with the Alzheimer's population Blog was found by searching the internet Interviews were distributed via e-mail Once the participants had responded, we analyzed the data and found common themes Data is reliable because we asked the same questions to each participant Descriptive validity Interpretive validity Internal validity Research Question Larger sample size to compare When working with this population (Alzheimer’s) the clients may have other pertaining health issues that affect the perceptions of the caregivers. Two of the three interviews were family members this could have caused a bias Not all health professions represented No information regarding feelings toward working with the different stages of Alzheimer’s Blog vs personal interview Conclusions & Implications 1. Use this information to help prepare health professionals who may be working with this population. a. Offer training on the stages of Alzheimer’s/Allen’s cognitive levels and what they may expect b. Use this information to prepare them for unpredictability and help them find ways to cope with it c. Knowing that they will experience anger and frustration, helping them to use this knowledge to be more prepared when they do d. By helping professionals know what to expect (emotions and functionally in their patients), this will help them to more effectively treat their clients when these instances arise (thereby improving outcomes).

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