RED AND BLUE
Transcript: Neoplasm Review Think Pyogenic Granuloma! RED AND BLUE -Exophytic nodule that has shown up recently -Covered by epithelium -Has blood vessels in it often means there is a coagulation issue Niacin deficiency = pellagra - can manifest as stomatitis and glossitis, with the tongue appearing red, smooth, and raw. NOTE: Sometimes, people just have a few, sporadic telangiectasias how to tell btwn hemangioma and vasc malformation? biopsy! -red and smooth dorsum of tongue Leukemia also looks like cherubism, brown's tumor, aneurysmal bone cyst greater than 2cm Same as petechiae but bigger What is it? -Autosomal Dominant -Abnormal vascular dilatations of terminal blood vessels DDX: Peutz-Jeghers Syndrome often means thrombocytopenia! Significance: brain lesions, gi lesions can lead to anemia, REQUIRES antibiotic prophylaxis palmar and plantar pits? nevoid basal cell carcinoma "gorlin syndrome" radiographic features: -commonly multilocular with honeycomb or soap bubble -can cause sunburst appearance (just like osteosarcoma) -use angiography to show vascular nature! -Acute and Chronic Myeloid Leukemia are most likely to show oral manifestations Overview Varix Pyogenic Granuloma Peripheral Giant Cell Granuloma Traumatic Hemangioma Congenital Vascular Malformations Syndromes ` accumulation of blood into tissues that produces a mass -recent onset (difference btwn this and hemangioma/ vascular malformation) Differentials for PGCG: Brown's Tumor of hyperparathyroidism: stones - kidney stones, calcifications bones - loss of lamina dura, ground glass abdominal groans - duodenal ulcers -Look for systemic features, like anemia, infections, neutropenia -Oral features include: gingival enlargement, petechiae, spontaneous gingival bleeding, ulcers Non-vascular neoplasm vascular neoplasm Petechiae Purpura Ecchymosis Hematoma Vit B deficiency Pernicious Anemia Iron deficiency anemia -associated with atrophy of tongue and angular chelitis -most commonly affects women ages 30-50 caused by release of RBCs into connective tissue vs osteosarcoma w/ sunburst appearance Hereditary hemorrhagic telangiectasia Pt needs to be checked for intestinal polyps - adenocarcinoma also at higher risk for developing breast cancer! Peripheral and Central look the same under the microscope. Whats the difference? Central starts in the bone, Peripheral is ALWAYS on the gingiva. Sturge-Weber Clinical Presentation: nosebleeds, GI bleeding, Port wine stains, seizures, small strokes Txm: excision to periosteum but can recur
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